Ah dont we all want to know that. There is no one sure way but here are some of the best: Lending:items like whips which can go for 25k an hour,dragon items,hoiladay items, and any other commonly sought after item,problem is that you'll have to lend them out a lot and buy them, but you could lend out things like wepons you already have when you dont need them etc. trianing non cobat skills. alchemy:good items to alc are yew and magic bows but you'll have to get the runes and logs yourself. shooting star from distractions and diversions. fishing items like lobsters,monkfish,sharks, selling dragon bones. dragon hides. barrows. treasure scroll rewards. smithing cannon balls.
this are but a few there are many others if these cant help check out money making on the runescape wiki